A First-Of-Its-Kind Bee Vaccine.
Dalan’s honeybee vaccine is delivered orally. The vaccine is ingested by the queen, and immunity is passed on to larvae for protection against diseases.
How it works
The Dalan vaccine technology exposes queen bees to inactive (i.e., “dead”) bacteria, which enables the larvae hatched in the hive to resist infection.
Dalan can assist in creating a custom vaccination program for your operation that is compatible with a variety of commonly used queen cages.
Available Now
USA and Canada
Two ways to protect your hives
1. Purchase the vaccine directly from Dalan
2. Purchase vaccinated queens from a certified queen producer
Purchase the vaccine directly from Dalan
Dalan representative will help determine the number of doses needed for your operation.
Vaccinate queens to protect newly hatched honeybee larvae against AFB using the new vaccine available from Dalan Animal Health. Available now in the USA and Canada. Recommended for beekeepers with 50 hives or more.

Product rendering only. For full information, see package insert.
Purchase vaccinated queens from a certified queen producer
Find a certified queen producer near you. Each producer offers Dalan’s vaccinated queens, ensuring your hives are protected. Simply select a location that suits you, and choose a producer based on your specific needs and preferences.
Videos and Publications
Everything you need to know about the first ever honeybee, from how it works, how to use it, and safety and efficacy data.
Step-by-step instructions for preparing the queen candy for vaccination.
Ian Steppler shares his method for vaccinating queens.
Dr. Humberto Boncristiani from Inside the Hive TV breaks down the findings of this new research and explains why it’s such a game-changer for beekeeping and honey bee health.
Why Vaccinate Your Honeybees?
Amy Franklin, MS, DVM
Contagious honey bee diseases can cause significant economic harm to the honey bee industry and devastate honey bee populations. For bacterial diseases, the use of antibiotics can result in bacterial resistance and negatively impact overall hive health. Vaccination can be a promising alternative to protect honey bee colonies and the food supply chain. Read the Article
A Commercial Perspective: February
American Bee Journal
In the February 2025 edition of American Bee Journal, commercial beekeeper Charles Linder shares his perspective on the critical role of innovation in the beekeeping industry, giving special recognition to Dalan’s vaccine. Read the Article
A Vaccine for Deformed Wing Virus?
American Bee Journal
A new vaccine for AFB may have wider benefits.
Read the Article
Control of Deformed Wing Virus-B in a Commercial Apiary Following Queen Vaccination with an Experimental Paenibacillus larvae Bacterin
Dalan Animal Health
Deformed Wing Virus (DWV) is a viral disease present in the majority of honey bee colonies worldwide. There is no available treatment or preventative for DWV, therefore management of the disease is limited to indirect mite control. In a 400-hive placebo-controlled field study, we demonstrated that colonies with queens vaccinated using an experimental Paenibacillus larvae bacterin have significantly reduced DWV-B loads compared to colonies with unvaccinated queens Download Whitepaper
The oral vaccination with Paenibacillus larvae bacterin can decrease susceptibility to American Foulbrood infection in honey bees—A safety and efficacy study
Frontiers in Veterinary Science
Pollination services to increase crop production are becoming more and more important, as we are facing both climate change and a growing world population. Both are predicted to impact food security worldwide. High-density, commercial beekeeping has become a key link in the food supply chain, and diseases have become a central issue in hive losses…
Download the publication
Learn more about Dalan’s Paenibacillus Larvae Bacterin vaccine