Media and Publications

Play Video

The Most Destructive Honey Bee Disease

Inside the Hive TV
Play Video

Honey bee queens vaccinate the young bees naturally

Inside the Hive TV

The oral vaccination with Paenibacillus larvae bacterin can decrease susceptibility to American Foulbrood infection in honey bees—A safety and efficacy study

Frontiers in Veterinary Science
Pollination services to increase crop production are becoming more and more important, as we are facing both climate change and a growing world population. Both are predicted to impact food security worldwide. High-density, commercial beekeeping has become a key link in the food supply chain, and diseases have become a central issue in hive losses…
Download the publication
Learn more about Dalan’s Paenibacillus Larvae Bacterin vaccine

Transgenerational Immune Priming

Dalan Animal Health
How insects pass immunity to their offspring.
Download the white paper

Immune pathways and defence mechanisms in honey bees Apis mellifera

Insect Molecular Biology
Social insects are able to mount both group-level and individual defences against pathogens. Here we focus on individual defences, by presenting a genome-wide analysis of immunity in a social insect, the honey bee Apis mellifera…
Read more at Insect Molecular Biology

The maternal transfer of bacteria can mediate trans-generational immune priming in insects

Parents invest in their offspring by preparing them for defense against pathogens and parasites that only the parents have encountered, a phenomenon known as trans-generational immune priming. We investigated the underlying mechanism using the established lepidopteran model host Galleria mellonella…
Read more at Virulence

Transfer of Immunity from Mother to Offspring Is Mediated via Egg-Yolk Protein Vitellogenin

PLOS Pathogens
Insect immune systems can recognize specific pathogens and prime offspring immunity. High specificity of immune priming can be achieved when insect females transfer immune elicitors into developing oocytes….
Read more at PLOS Pathogens

The role of Vitellogenin in the transfer of immune elicitors from gut to hypopharyngeal glands in honey bees (Apis mellifera)

Journal of Insect Physiology
Female insects that survive a pathogen attack can produce more pathogen-resistant offspring in a process called trans-generational immune priming. In the honey bee (Apis mellifera), the egg-yolk precursor protein Vitellogenin transports fragments of pathogen cells into the egg, thereby setting the stage for a recruitment of immunological defenses prior to hatching….
Read more at the Journal of Insect Physiology