The beekeeper treats the bees of the varroa mite. Diseases of bees and their treatment. Varroasis. Varroa destructor

Veterinary Resources

Honeybees play a significant role in agriculture and food production and are rightfully classified as livestock. As such, they require the same type of veterinary resources as livestock to thrive. As honeybee veterinarians, your role in preserving the health and population of honeybees is significant. By providing guidance, medical expertise, and support to beekeepers, you contribute to the conservation of honeybees and the ecosystem that needs their support.

As a veterinarian involved in honeybee health, you’re trained to diagnose and treat diseases affecting honeybee colonies. This includes identifying bacterial, fungal, and viral diseases, and providing medical expertise on how to prevent and treat these diseases. One such disease includes the highly contagious bacterial disease, American Foulbrood (AFB). 

This is where Dalan’s innovative AFB vaccine can be an indispensable veterinary resource for practitioners.

How You Can Help Control American Foulbrood Disease (AFB)

American Foulbrood is a bacterial disease caused by the spore-forming bacterium Paenibacillus larvae. In the U.S., AFB outbreaks had previously been controlled with the routine use of antibiotics. However, heavy antibiotic usage has its own consequences, such as bacterial resistance and negative effects on overall hive health. In 2017, the FDA eliminated the prophylactic use of antibiotics, leaving the industry without an effective solution.

Dalan’s prophylactic and sustainable approach aims to decrease the risk of infections, saving not only hives, but protecting from revenue loss and excess costs. 

How to Use the Vaccine

When queen bees are fed Dalan’s oral vaccine, protection works through a biological mechanism called Transgenerational Immune Priming (TGIP), whereby the queen passes immunity to her daughters before they hatch. Dalan’s vaccine exposes queen bees to inactivated P. larvae, which enables the larvae hatched in the hive to resist infection to AFB.


How it works

The Dalan vaccine technology exposes queen bees to inactive (i.e., “dead”) bacteria, which enables the larvae hatched in the hive to resist infection.

Dalan can assist in creating a custom vaccination program for your operation that is compatible with a variety of commonly used queen cages.

The vaccine is mixed with queen candy.
Worker bees consume the vaccine with the queen candy which is then digested and transferred to the glands that produce the royal jelly.
Worker bees feed the royal jelly containing the vaccine to the queen bee.
The queen digests the royal jelly and the vaccine is transferred to her ovaries. She is then released into the hive.
The vaccine is transferred to the developing eggs.
The developing larvae (now vaccinated) are more immune to infection as they hatch.
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Our vaccine is conditionally licensed by the USDA-CVB and CFIA-CCVB for the vaccination of queen honeybees to prime larvae against mortality due to Paenibacillus larvae.

Dalan’s AFB vaccine can help ensure the health and survival of honeybee colonies, making it an essential veterinary resource. Here are some of the ways Dalan’s AFB vaccine can benefit honeybee veterinarians:

Enhanced Client Services

Offering an AFB vaccination service for honeybee colonies can enhance the range of services provided by honeybee veterinarians. By offering this service, veterinarians can better serve their clients and contribute to the overall health and sustainability of honeybee populations.

Education and Outreach

Honeybee veterinarians have the unique opportunity to educate beekeepers about the benefits of vaccination as part of their disease prevention strategies. By raising awareness about the availability and effectiveness of our AFB vaccine, veterinarians can empower beekeepers to make informed decisions about protecting their colonies against AFB.

Improved Disease Management

Our vaccine offers honeybee veterinarians a new tool for managing AFB. By providing a means of prevention, the vaccine may help veterinarians reduce the economic losses and environmental impact associated with AFB outbreaks.

These reasons and more are why honeybee veterinarians are encouraged to consider Dalan’s AFB vaccine as part of their disease mitigation strategies. Take the proactive step to help safeguard your client’s honeybee colonies from AFB by contacting Dalan today for more information on all our resources. 

Purchasing the Vaccine

United States

A prescription is not required for use of the vaccine in the United States. Beekeepers in the US can acquire the vaccine directly from Dalan, or from their Veterinarian’s office. If you are interested in carrying the vaccine in your practice, please contact Dalan for a quote today.


A prescription is required for use of the vaccine in Canada. Beekeepers interested in purchasing the vaccine from Dalan will need to present a signed Veterinarian prescription to order. For more product information, you can view our package insert or contact us today. If you are interested in carrying the vaccine in your practice, please contact Dalan for a quote today.

Frequently Asked Questions

American Foulbrood is a bacterial disease caused by the spore-forming bacterium Paenibacillus larvae. The disease-causing bacteria can be present at subclinical levels in hives which can erupt at any time. Infective spores may last in the environment for several decades.

The vaccine, containing a killed pathogen, is administered orally to the queen honeybee. Attendants caged with the queen are fed queen candy containing the vaccine. Work carried out in Dalan’s laboratories has indicated that the attendants digest the vaccine and produce royal jelly containing vaccine particles. The royal jelly is fed to the queen, and as she ingests it, pieces of the vaccine are transported via her fat body to her ovaries where it is deposited in the eggs. The developing larvae are exposed to the vaccine and start to build up immunity before they hatch.

Dalan’s AFB vaccine offers a prophylactic, non-chemical approach to managing AFB. It focuses on maintaining hive health preventatively, providing a safer and more cost-effective solution in the long run.

In the United States, beekeepers do not need a prescription to purchase the vaccine. 

In Canada, beekeepers do need a prescription from a Veterinarian to purchase the vaccine. For more product information, you can view our package insert or contact us today.

Yes, the vaccine is suitable for use in organic agriculture. It is non-GMO and does not contain any chemicals or harmful preservatives.

To request a quote, please contact us today. 

Additional Resources


Veterinary Webinar

Dalan Animal Health presents an informational webinar discussing the science behind the first vaccine for honeybees, how it can be used in hives, and how Veterinarians can now offer this new tool to their beekeeping clients.